A drug delivery method that uses one of the body’s own systems to sneak mRNA molecules across the blood-brain barrier could help treat diseases like Parkinson’s, Alzheimer’s and cancer
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December 23, 2022
Getting drugs into the brain to treat disease is difficult Andrew Brooks/Westend61/Getty Images
A way to sneak messenger RNA molecules into the brain could help us treat neurodegenerative diseases and brain tumors.
Diseases affecting the brain can be difficult to treat because blood brain barrierwhich prevents pathogens in our blood from reaching our brains and also prevents the passage of large, potentially therapeutic molecules such as mRNA.
Now, Gu Wenchao at Cornell University in New York and her colleagues developed an approach based on the recent discovery of innate virus-like particles in…